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Theses and Dissertations
This collection contains theses and dissertations of graduate students of the University of Alberta. The collection contains a very large number of theses electronically available that were granted from 1947 to 2009, 90% of theses granted from 2009-2014, and 100% of theses granted from April 2014 to the present (as long as the theses are not under temporary embargo by agreement with the Faculty of Graduate and Postdoctoral Studies). IMPORTANT NOTE: To conduct a comprehensive search of all UofA theses granted and in University of Alberta Libraries collections, search the library catalogue at www.library.ualberta.ca - you may search by Author, Title, Keyword, or search by Department.
To retrieve all theses and dissertations associated with a specific department from the library catalogue, choose 'Advanced' and keyword search "university of alberta dept of english" OR "university of alberta department of english" (for example). Past graduates who wish to have their thesis or dissertation added to this collection can contact us at erahelp@ualberta.ca.
Items in this Collection
- 15Multiple Sclerosis
- 2Experimental autoimmune encephalomyelitis
- 2Iron
- 2Neurotransmitters
- 2Phenelzine
- 15-HT
- 1Chadwick, Caylin Isabelle
- 1Deng, Xiaodan
- 1Deslauriers, Andre
- 1Elkady, Ahmed
- 1Frieser, Emma CG
- 1Jonzon, Alison Jill
- 4Department of Biomedical Engineering
- 3Centre for Neuroscience
- 2Neuroscience
- 1Department of Biochemistry
- 1Department of Mathematical and Statistical Sciences
- 1Department of Medical Microbiology and Immunology
- 2Kerr, Bradley (Anesthesiology & Pain Medicine)
- 2Wilman, Alan (Biomedical Engineering)
- 1Beaulieu, Christian (Radiology & Diagnostic Imaging, Biomedical Engineering)
- 1Carroll, Linda (School of Public Health)
- 1Davenport, Margie (Kinesiology, Sport and Recreation)
- 1Dr. Bradley Kerr (Anesthesiology and Pain Medicine)
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Fall 2024
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by central nervous system (CNS) lesions, resulting in axonal loss and physical and cognitive disability. Loss of myelin sheath known as demyelination, is followed by its regeneration in a process, known as remyelination, that...
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Amino acid and biogenic amine concentrations during experimental autoimmune encephalomyelitis and the disease-modifying effects of phenelzine treatment
DownloadFall 2011
The project described in this thesis began with a broad analysis of the changes to amino acid and biogenic amine concentrations in the central nervous system (CNS) during experimental autoimmune encephalomyelitis (EAE) in mice, an animal model of Multiple Sclerosis (MS). That study identified...
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Fall 2022
Calnexin is a type 1 integral endoplasmic reticulum (ER) membrane protein and molecular chaperone involved in the folding and quality control of membrane associated and secreted proteins. The ER luminal domain of calnexin is responsible for the chaperone function, whereas the C-terminal domain is...
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Chronic Pain in a Mouse Model of Multiple Sclerosis: Contributions of the Kappa Opioid System
DownloadFall 2021
The perception of pain is a multimodal experience that is encoded by regions of the central nervous system (CNS) that are involved in sensation, affect, and cognition. Chronic pain is not merely the persistence of pain, but a debilitating condition that is associated with neurochemical...
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Fall 2010
This study described the play experiences of daughters who were caregivers to their mothers with multiple sclerosis (MS). The experiences of four Canadian-Caucasian women aged 19-26 were captured using phenomenological methods of individual and focus group interviews, field notes, and artefacts....
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Development and Application of Quantitative Gradient-Echo MRI Techniques for Assessment of Iron and Myelin in the Multiple Sclerosis Brain
DownloadFall 2018
Multiple Sclerosis (MS) is a progressive autoimmune and neurodegenerative disease of the Central Nervous System that results in demyelination and neuronal/axonal loss. Along with clinical evaluation, Magnetic Resonance Imaging (MRI) is the gold standard modality for diagnosing and monitoring MS,...
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Fall 2013
Magnetic resonance imaging (MRI) is a valuable imaging modality and is commonplace in diagnosing, evaluating, and understanding the pathobiology of many neurological disorders. Current methods are helpful in the diagnosis of multiple sclerosis (MS) but fail to provide useful longitudinal...
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Diffusion Magnetic Resonance Imaging Tractography of the Fornix in Pediatric and Adult Multiple Sclerosis
DownloadFall 2024
The fornix is the main white matter output tract of the hippocampus and part of the limbic system, which is involved in aspects of memory and cognition. High-resolution, fluid-suppressed diffusion tensor imaging tractography has identified marked volume and diffusion abnormalities of the fornix...
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Endoplasmic reticulum stress induction by an endogenous retrovirus glycoprotein during neuroinflammation: regulation by a free radical scavenger
DownloadFall 2010
Endoplasmic reticulum (ER) stress is a homeostatic mechanism, which is utilized by cells to adapt to inter- and intra-cellular changes. There is a burgeoning literature showing that the human endogenous retroviral envelope glycoprotein, Syncyin-1, oxidative stress and reactive oxygen species...
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Fall 2011
Functional data analysis (FDA) is a fast-growing area in statistics with the aim of estimating a set of related functions or curves rather than focusing on a single entity, like estimating a point, as in classical statistics. FDA has a wide range of applications in different fields such as...