Research Data and Materials (Chemistry)

2012

de la Mata, A. P., Harynuk, J. J., Sinkov, N.A.

Interesting real-world samples are almost always present as mixtures containing the analyte(s) of interest and a matrix of components that are irrelevant to answering the analytical question at hand. Additionally, the compounds comprising the matrix are usually present in far greater...

2011-11-30

Murphy, Jeffrey N.

In order to adapt images of patterns templated using block copolymers, acquired using a scanning electron microscope, for publication, an algorithm was developed to process the images, enhancing the darker features in a consistent and easily reproducible manner. This was done using ImageJ, a free...

2007

Fusco P. C., Bundle, D. R., Ling, C.-C., Michon, F., Moore, S. L., Uitz, C.

Previous studies have identified the length dependency of several polysaccharide (PS) protective epitopes. We have investigated whether meningococcal polysaccharides Y and W-135 possess such epitopes. Oligosaccharides (OSs) consisting of one or more disaccharide repeating units (RU) were derived...

2020-06-01

Cairo, Christopher W.

List of known human neuraminidase inhibitors reported or tested by the Cairo group (University of Alberta). List is filtered to compounds with notable potency or selectivity. Compounds are assigned unique identifiers and linked to PubChem identifiers.

2011

Mulvey, G. L., Bundle, D. R., Deng, Z., Armstrong, G. D., Sadowska, J .M., Paszkiewicz, E., Griener, T., Ahmed, M., Narain, R., Kitov, P. I.

Inhibition of AB(5)-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin's pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid P component, of the innate immune system....

2016-06-22

Jia, Feng, Howlader, Md. Amran, Cairo, Christopher W.

Integrins are critical receptors in cell migration and adhesion. A number of mechanisms are known to regulate the function of integrins, including phosphorylation, conformational change, and cytoskeletal anchoring. We investigated whether native neuraminidase (Neu, or sialidase) enzymes which...

2015-09-16

Heranadez Armada, Daniel, Santos, Jobette T., Richards, Michele R., Cairo, Christopher W.

A variety of applications in glycobiology exploit affinity chromatography through the immobilization of glycans to a solid support. Although several strategies are known, they may provide certain advantages or disadvantages in how the sugar is attached to the affinity matrix. Additionally, the...

2014-07-05

Murphy, Jeffrey N.

Scanning electron microscope (SEM) images of patterns derived from polystyrene-block-poly(2-vinylpyridine), where the poly(2-vinylpyridine) domains replaced with platinum metal. All samples were annealed for 20 minutes at 200 degrees celsius. Polymers used include PS(23.6k)-b-P2VP(10.4k),...

2012

Cutler, J. E., Dziadek, S., Bundle, D. R., Cartmell, J., Xin, H., Bailey, J. J.

Our research on pathogenesis of disseminated candidiasis led to the discovery that antibodies specific for Candida albicans cell surface b-1, 2–mannotriose [b-(Man)3] protect mice. A 14 mer peptide Fba, which derived from the N-terminal portion of the C. albicans cytosolic/cell surface protein...

2017-04-18

Mariusz Klobukowski

These basis sets were prepared using the new well-tempered formula introduced by S. Huzinaga and B. Miguel (Chem. Phys. Lett., 175 (1990) 289-291): ζ(N) = α ζ(N−k+1) = ζ(N−k+2) * β * [ 1+ γ (k/N)^δ ] , k = 2, ... ,N where α, β, γ, and δ are parameters (common for the radial functions of all...