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Journal Articles (Chemistry)
Items in this Collection
- 14Loppnow, Glen R.
- 5El-Yazbi, Amira F.
- 2Nair, Sindhu G.
- 2Shoute, Lian C. T.
- 2Teimoory, Faranak
- 1Azimi, Shakiba
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2013-01-01
Nair, Sindhu G., Loppnow, Glen R.
The exposure of DNA to ultraviolet (UV) radiation causes sequence‐dependent damage. Thus, there is a need for an analytical technique that can detect damage in large numbers of DNA sequences simultaneously. In this study, we have designed an assay for UVC‐induced DNA damage in multiple...
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2018-01-01
El-Yazbi, Amira F., Loppnow, Glen R.
Hepatocellular carcinoma is one of the most common malignant tumors in the world. Chronic hepatitis B and C infections are the most common etiologies of hepatocellular carcinoma worldwide. In this study, we explore the potential DNA damaging effect of some FDA-approved antiviral drugs which may...
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Resonance Raman Intensities Demonstrate that C5 Substituents Affect the Initial Excited-state Structural Dynamics of Uracil More than C6 Substituents
Download2016-01-01
Teimoory, Faranak, Loppnow, Glen R.
Resonance Raman derived initial excited‐state structural dynamics provide insight into the photochemical mechanisms of pyrimidine nucleobases, in which the photochemistry appears to be dictated by the C5 and C6 substituents. The absorption and resonance Raman spectra and excitation profiles of...
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Terbium fluorescence as a sensitive, inexpensive probe for UV-induced damage in nucleic acids
Download2013-01-01
El-Yazbi, Amira F., Loppnow, Glen R.
Much effort has been focused on developing methods for detecting damaged nucleic acids. However, almost all of the proposed methods consist of multi-step procedures, are limited, require expensive instruments, or suffer from a high level of interferences. In this paper, we present a novel simple,...