Journal Articles
Items in this Collection
- 3Lunney, Joan K.
- 2Harding, John C. S.
- 2Plastow, Graham S.
- 1Bannister, Stephanie
- 1Bao, Hua
- 1Daujotyte, Dalia
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Differences in Whole Blood Gene ExpressionAssociated with Infection Time-Course andExtent of Fetal Mortality in a ReproductiveModel of Type 2 Porcine Reproductive andRespiratory Syndrome Virus (PRRSV)Infection
Download2016-04-19
Wilkinson, Jamie M., Ladinig, Andrea, Bao, Hua, Kommadath, Arun, Stothard, Paul, Lunney, Joan K., Harding, John C. S., Plastow, Graham S.
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnantfemales causes fetal death and increased piglet mortality, but there is substantial variationin the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
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Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection
Download2020-01-01
Van Goor, Angelica, Pasternak, Alex, Walker, Kristen, Hong, Linjun, Malgarin, Carolina, MacPhee, Daniel J., Harding, John C. S., Lunney, Joan K.
Background:A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However,the mechanisms leading to variation in fetal outcome in response to PRRSV...
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2019-01-01
Lim, Kyu-Sang, Dong, Qian, Moll, Pamela, Vitkovska, Jana, Wiktorin, Gregor, Bannister, Stephanie, Daujotyte, Dalia, Tuggle, Christopher K., Lunney, Joan K., Plastow, Graham S., Dekkers, Jack C. M.
Background:Gene expression profiling in blood is a potential source of biomarkers to evaluate or predict phenotypic differences between pigs but is expensive and inefficient because of the high abundance of globin mRNA in porcine blood. These limitations can be overcome by the use of QuantSeq...