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2010 2nd Annual Celebration of Research and Innovation
Items in this Collection
- 1Cell cycle/physiology
- 1Myosin Heavy Chains/metabolism
- 1Myosin Type V/metabolism
- 1Peroxisomes
- 1Peroxisomes/metabolism
- 1Receptor-cargo complexes
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2009
Knoblach, B., Mast, F.D., Weisman, L.S., Glover, J.N.M., Logan, M.R., Eitzen, G.A., Rachubinski, R.A., Brunner, M.J., Fagarasanu, A., Atichison, J.D., Jin, Y.
In Saccharomyces cerevisiae, the class V myosin motor Myo2p propels the movement of most organelles. We recently identified Inp2p as the peroxisome-specific receptor for Myo2p. In this study, we delineate the region of Myo2p devoted to binding peroxisomes. Using mutants of Myo2p specifically...
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2010
Rachubinski, R.A., Fagarasanu, A., Mast, F.D.
Peroxisomes can import large multimeric protein complexes and even 9-nm gold particles decorated with peroxisome-targeting signals. They achieve these feats of protein passage using a distinctive translocon whose highly dynamic aqueous pore can expand to accommodate the increasing girths of...