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Journal Articles (Biochemistry)
Items in this Collection
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Regulation of Na+/H+ Exchanger Gene Expression: Role of a poly T rich region in regulation of expression of the NHE1 promoter
Download1996-01-01
Yang, Weidong, Wang, Huayan, Fliegel, Larry
In this study we examine regulation of expression of the Na+/H+ exchanger promoter in L6 and NIH 3T3 cells. We have identified a highly conserved poly(dA·dT)-rich region that appears to be important in regulation of expression of the NHE1 gene. Deletion or mutation of this region results in...
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The Na+/H+ exchanger potentiates growth and retinoic acid induced differentiation of embryonal carcinoma cells
Download1997-01-01
Wang, Huayan, Singh, Dyal, Fliegel, Larry
The Na+/H+exchanger is a ubiquitous plasma membrane protein that is responsible for pH regulation and is activated by growth factors. We examined the role of the Na+/H+ exchanger in cell growth and differentiation. Treatment of P19 cells with the Na+/H+ exchanger inhibitor Hoe 694 eliminated...