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Journal Articles (Biochemistry)
Items in this Collection
- 1Alanine Scanning Mutagenesis
- 1Antiporter
- 1Cation Coordination
- 1Circular-Dichroism Spectra
- 1Functional-Characterization
- 1Heterologous Expression
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Dimeric structure of human na+/H+ exchanger isoform 1 overproduced in saccharomyces cerevisiae
Download2008-01-01
Moncoq, Karine, Kemp, Grant, Li, Xiuju J., Fliegel, Larry, Young, Howard S.
The Na+/H+ exchanger isoform 1 (NHE1) is an integral membrane protein that regulates intracellular pH by extruding an intracellular H+ in exchange for one extracellular Na+. The human NHE1 isoform is involved in heart disease and cell growth and proliferation. Although details of NHE1 regulation...
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Structural and functional analysis of transmembrane segment IV of the salt tolerance protein Sod2
Download2013-01-01
Ullah, Assad, Kemp, Grant, Lee, Brian, Alves, Claudia, Young, Howard, Sykes, Brian D., Fliegel, Larry
Sod2 is the plasma membrane Na+/H+ exchanger of the fission yeast Schizosaccharomyces pombe. It provides salt tolerance by removing excess intracellular sodium (or lithium) in exchange for protons. We examined the role of amino acid residues of transmembrane segment IV (TM IV)...