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Optimization, adaptation and application of protein misfolding cyclic amplification to detection of prions in blood plasma
DownloadFall 2010
The PMCA assay was optimized for adaptation to low level detection of PrPSc in hamster plasma. Evaluation of numerous key variables of the PMCA assay led to an optimized protocol capable of ~3 log10 amplification after 32 cycles (two 16 hour rounds). When commercially purchased normal hamster...
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Orally Administered P22 Phage Tailspike Protein Reduces Salmonella Colonization in Chickens: Prospects of a Novel Therapy against Bacterial Infections
Download2010
Henry, M., Tanha, J., Foss, M., Ryan, S., Masotti, M., Coleman, R., Hanifi-Moghaddam, P., MacKenzie, R., Waseh, S., Szymanski, C.M.
One of the major causes of morbidity and mortality in man and economically important animals is bacterial infections of the gastrointestinal (GI) tract. The emergence of difficult-to-treat infections, primarily caused by antibiotic resistant bacteria, demands for alternatives to antibiotic...
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Spring 2010
The majority of workers in the Hudson’s Bay Company, up until the mid-19th century, originated in the Orkney Islands, off the north coast of Scotland. Historians have characterized these workers as an homogenous group—thrifty, sober, suited to work in cold weather and in the boats. Most worked...
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Orthochromic Normoblast - 3
2010-12-10
An image from a bone marrow demonstrating an orthochromic normoblast with a condensed nucleus (labeled)
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Orthodontic bracket manufacturing tolerances and dimensional differences between select self-ligating brackets
Download2010
Nobes, David S., Carey, Jason P., Major, Paul W., Major, Thomas W.
In all manufacturing processes there are tolerances; however, orthodontic bracket manufacturers seldom state the slot dimensional tolerances. This experiment develops a novel method of analyzing slot profile dimensions using photographs of the slot. Five points are selected along each wall, and...