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4-aminobenzoic acid hydrazide mediated inhibition of Microperoxidase-11: catalytic inhibition by reactive metabolites.Download
Currently, there is lack of clinical therapeutics for inhibiting myeloperoxidase mediated pathogenesis. We used 4-aminobenzoic acid hydrazide (4-ABAH), the most potent irreversible inhibitor of myeloperoxidase and microperoxidase-11 to obtain mechanistic insight on the role of reactive...
Macrophages are the primary cells of innate immunity that provide the first line of defence against any external stimuli. Their phagocytic properties enable them to engulf invading microbes or foreign particles. The phagocytic capability of macrophages plays a major role in interfering with drug...