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ENDOTHELIAL CELL HETEROGENEITY: A CORRELATION WITH THE VON WILLEBRAND FACTOR EXPRESSION IN DISTINCT ORGANS
DownloadSpring 2017
Endothelial cells (EC) of different organs exhibit heterogeneity in structure, function and gene expression pattern. This also extends to the pattern in which the highly endothelial-specific gene, von Willebrand Factor (VWF) is expressed. VWF is a multimeric adhesive, pro-coagulant glycoprotein...
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Fall 2019
Background Islet transplantation is an attractive alternative treatment for type 1 diabetes mellitus (T1DM). However, further application of islet transplantation in the clinic is limited by the shortage of human organ donors and the immune-mediated rejection. Neonatal pig islets (NPI) are being...