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Fall 2009

Lee, Megan Sae Bom

The C-terminal region of breast cancer susceptibility gene 1 (BRCA1) contains a pair of tandem BRCT repeats that are critical for the tumour suppressor function of BRCA1. BRCT repeats are present in a large of number of proteins that are implicated in the cellular response to DNA damage. A subset...

Fall 2012

Wong, Joyce JW

Bacterial conjugation is the process of plasmid DNA transfer from a donor cell to a recipient cell. This process is mediated in F-like plasmids by proteins expressed by the tra operon. The relaxosome forms at oriT (origin of transfer), where the nicking and unwinding of a single-stranded copy of...