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High throughput genotyping of single nucleotide polymorphisms in the Plasmodium falciparum dhfr and dhps genes by asymmetric PCR and melt-curve analysis
DownloadFall 2011
Mutations within Plasmodium falciparum dihydrofolate reductase (pfdhfr) and dihydropteroate synthase (pfdhps) genes contribute to resistance to antimalarials such as sulfadoxine-pyrimethamine (SP). Single nucleotide polymorphisms (SNPs) within codons 51, 59, 108 and 164 in the pfdhfr gene and...
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Using Malaria Rapid Diagnostic Tests in Ghana: Understanding Healthcare Providers' Compliance with Policy Guidelines for Malaria Diagnosis in Peripheral Facilities
DownloadSpring 2014
Financing and implementation of malaria control measures expanded vastly over the past decade, leading to substantial reductions in global malaria morbidity and mortality. Yet malaria still threatens health and socio-economic development among the poorest populations particularly in sub-Saharan...