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Investigation of banglenes as neurotrophic agents and development of a new fluorescent protein- based FRET pair
DownloadFall 2022
This thesis describes efforts towards understanding the neurotrophic activity of banglenes and the development of a new fluorescent protein-based FRET pair. Neurotrophic small molecule natural products are functional analogs of signaling proteins called neurotrophins, which cause a pro-growth,...
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Modular Design and Directed Evolution for the Development of Genetically Encodable Fluorescent Sensors
DownloadSpring 2019
The development of genetically encodable sensors for optical imaging has revolutionized the way researchers investigate cellular phenomena. Illuminating the molecular dynamics of the cell has become nearly routine with countless improvements in sensor design and directed evolution efforts to...