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- 1Biosensors
- 1FRET response optimization
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Development and optimization of a high through-put screening methodology for rapid dynamic range improvement of FRET-based biosensors
DownloadSpring 2012
Abdel Latif Ibraheem, Ahmed Abdel Mohsen
Fluorescent protein (FP)-based biosensors based on the principle of intramolecular Förster resonance energy transfer (FRET) enable the visualization of a variety of biochemical events in living cells. The sensitivity of such biosensors is proportional to the change in ratiometric emission, and so...
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Fall 2014
The discovery and subsequent applications of fluorescent proteins (FPs) launched a new era for live cell fluorescence imaging. The design and developments of FP-based indicators have further solidified the versatility of FPs and rendered them as indispensable tools in life science research now...
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Expanding the optogenetic toolkit with a photocleavable protein and a near infrared pH indicator
DownloadFall 2017
Optogenetics is an emerging biological technique that is causing a revolution in life science. It uses optical methods to control and visualize genetically targeted biological events in a relatively non-invasive and spatiotemporally precise manner. Optogenetics requires advanced optical...