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Skip to Search Results- 1ATP-Sensitive Potassium Channel
- 1ATP-sensitive potassium channel
- 1Heart disease
- 1Patch clamping
- 1Pharmacogenomics
- 1Pharmacology
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Spring 2011
The cardiac sodium-calcium exchanger (NCX) is an important membrane protein which regulates cellular calcium necessary for the optimal contractile function of the heart. NCX has become a focal point in ischemic heart disease (IHD) research as evidence suggests that reactive oxygen species (ROS)...
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Spring 2012
The common ATP-sensitive (KATP) channel variants E23K and S1369A, found in the KCNJ11 and ABCC8 genes respectively, form a haplotype that is associated with an increased risk for type 2 diabetes. Our previous studies showed that KATP channel inhibition by the A-site sulfonylurea gliclazide was...