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(RADA)4 Self-Assembling Peptide based Hydrogels: Design, Characterization and In-Vitro Biological Evaluation
DownloadFall 2016
Ionic self-assembling peptides have emerged as promising nano-biomaterials, with direct applications in the fields of bioengineering and applicative medicine. (RADA)4 is a self-assembling 16 residue containing peptide, with alternating hydrophobic and hydrophilic residues. This characteristic...
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Fall 2013
Protein adsorption at the biomaterial-tissue interface has several detrimental consequences which undermines the widespread application of engineered materials. Herein, it was asked what role protein secondary structures play in the adsorption of peptides, as well as how these structures affect...
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Fall 2024
Protein adsorption to implanted biomaterials can direct host responses and lead to health complications and device failure. Polyethylene oxide (PEO) is the gold standard film for reducing non-specific protein adsorption. Although polymer chain density is an important factor in determining PEO’s...
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Fall 2017
Inflammation is generally considered to be a protective response, however the effects of inflammation can also be harmful and even fatal. The study of regulating the inflammatory response in damaged tissue by using engineered biomaterials is not only essential for enhancing the biocompatibility...
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Spring 2021
Impaired vision and blindness are serious global health problems that affect vast numbers of the population. The impact of ocular diseases is more severe in under-developed countries where, due to the lack of or limited access to vision care, many preventable or curable ocular diseases lead to...