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Galactose-Decorated Polymers and Nanogels Synthesized via Reversible Addition-Fragmentation Chain Transfer Polymerization for in vitro Tumor Targeted Drug Delivery and Gene Knockdown
DownloadSpring 2016
The first part of this thesis focuses on the synthesis and development of thermosensitive galactose-based nanogels, evaluating their potential in encapsulating and releasing Iodoazomycin Arabinofuranoside (IAZA), a clinical drug for imaging solid hypoxic tumors, for its hypoxia-selective...
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Spring 2016
Protein–carbohydrate interactions are involved in a wide variety of cellular recognition processes including cell growth regulation, differentiation and adhesion, immune response, and viral or bacterial infections. Recently, utilization of carbohydrate based polymers and nanomaterials for various...