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Skip to Search Results- 2Parkinson's disease
- 2intramembrane proteolysis
- 2rhomboid protease
- 1PARK6
- 1PARL
- 1PARL-mediated cleavage
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Spring 2019
Intramembrane proteolysis is the process by which membrane-embedded proteases cleave substrates that are also embedded within the lipid bilayer or lie near to the bilayer. Rhomboid intramembrane proteases are a ubiquitous superfamily of serine intramembrane proteases that play a role in a wide...
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Spring 2019
PINK1 (Phosphatase-Tensin homologue (PTEN)-induced putative kinase 1) is a protein kinase heavily involved in mitochondrial health and integrity. It has multiple domains: an N-terminal mitochondrial targeting sequence, a transmembrane domain, and a kinase domain. Some mutations, located...