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- 1DNA repair
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Novel Therapeutic Approaches for Cancer Therapy Based on Targeting the Human DNA Repair Enzyme Polynucleotide Kinase/Phosphatase
DownloadFall 2018
The relentless growth of tumors is triggered by a complex array of molecular changes such as DNA damage, disruption of cell-cycle progression, uncontrolled proliferation and escaping cell death. Various therapies have been developed to treat cancer, many of which kill cancer cells by damaging...
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Unmasking the in vivo importance of STAT3 in multiple myeloma using three-dimensional culture and nanoparticle drug delivery system
DownloadSpring 2019
Multiple myeloma (MM) is a hematological malignancy which is caused by aberrant accumulation of monoclonal plasma cells (PCs) within the bone marrow. The oncogenesis of MM is mediated by chromosomal aberrations as well as the tumor microenvironment in the bone marrow. Signal transducer and...