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Transcatheter Aortic Valve Implantation (TAVI) for the Treatment of Aortic Valve Stenosis: a Systematic Review
DownloadSpring 2015
Introduction: Aortic stenosis (AS) is the most common form of heart valve disease in the western world. As the population ages, this disease is becoming an increasing burden on patients and on the health care system. Current drug therapies (medical management (MM)) cannot reverse the course of...
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Spring 2022
Ovarian cancer is the most lethal gynecological cancer, and epithelial ovarian cancer (EOC) accounts for about 90% of ovarian cancers. Despite advancements in medical technology, the overall survival rate of EOC has improved only slightly, with a 5-year survival rate of less than 50%. One cause...
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Transcription Factor FOXC1 Deregulates BMP-SMAD Signalling During Osteoblast Differentiation
DownloadFall 2016
Skeletal development is a tightly regulated process that continues through adulthood in the form of bone remodeling. Many bones of the appendicular and axial skeleton develop using a cartilage intermediate in a process called endochondral ossification. The cranial and flat bones of the skeleton...
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Transcriptional Control of Auxin-Transport-Dependent Vein Patterning in Arabidopsis thaliana
DownloadSpring 2020
Most multicellular organisms solve the problem of long-distance transport of signals and nutrients by means of tissue networks such as the vascular system of vertebrate embryos and the vein network of plant leaves; therefore, how vascular networks form is a key question in biology. In...