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Skip to Search Results- 1Baddam, Pranidhi
- 1Bahojb Habibyan, Yasaman
- 1Berlin-Broner, Yuli
- 1Bozorgmehr, Najmeh
- 1Crossman, Jacqueline
- 1Crossman, Jacqueline J
- 2Chronic Lymphocytic Leukemia
- 2Low intensity pulsed ultrasound
- 2T cell exhaustion
- 2microbiome
- 1Animal model
- 1Arthritis
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Fall 2016
Crohn’s disease (CD) is one of the chronic inflammatory bowel diseases (IBD) with a complex etiology involving genetic factors, priming by enteric microflora, environmental factors and a change in the immune-mediated response, the other IBD is ulcerative colitis. The diagnosis of CD has...
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Fall 2018
Background and Objectives: Atherosclerosis is a chronic inflammatory process which leads to heart disease and death. Apical periodontists (AP) is a common inflammatory condition associated with infected teeth. In a recent systematic review, we identified a positive association between AP and...
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Bone Morphogenetic Protein 7 Regulates Nasal Cartilage Properties Under Physiological And Pathological Conditions
DownloadFall 2021
Background: The nasal septum is a cartilaginous structure that provides critical structural and growth support for the midface. Nasal septum deviation (NSD) is a relatively frequent abnormality, which can be associated with nasal airway obstruction and disordered breathing in children. Although...
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Cellular Long Chain Fatty Acid Uptake by CD36: Identifying an Amino Acid That Plays a Critical Role and Assessing Physiological Impact in Bone Marrow Derived Macrophages
DownloadSpring 2021
Long chain fatty acids (LCFA) serve essential functions in human cells, and the presence of too little or too much could have detrimental effects. LCFA can enter cells through passive diffusion, also known as flip-flop, but the majority enter in association with a protein allowing regulation and...
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Differential signature of the microbiome and neutrophils in the oral cavity of HIV-infected individuals
DownloadSpring 2022
HIV infection is associated with a wide range of changes in microbial communities and immune cell components of the oral cavity. The purpose of this study was to evaluate the oral microbiome in relationship to oral neutrophils in HIV-infected compared to healthy individuals. We evaluated oral...
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Effect of low intensity pulsed ultrasound on orthodontically induced root resorption caused by torque: A prospective double blinded controlled clinical trial
DownloadFall 2015
Orthodontically induced root resorption (OIIRR) is an undesirable consequence of orthodontic treatment and may lead to permanent loss of root structure. A previous clinical trial demonstrated the effect of LIPUS on tipping type of OTM and reported that LIPUS can promote cementogenesis. However,...
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Elucidating how HIV-1 infection influences CD4, CD8 and regulatory T cell phenotype and function
DownloadFall 2021
Human Immunodeficiency Virus (HIV) infection is still a global health issue. Although the advent of highly active antiretroviral therapies (HAART) to suppress viral replication has transformed HIV infection from a lethal disease to a chronic and manageable infection, it does not cure HIV. CD8 T...
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Fall 2018
Background: Aggressive periodontitis (AgP) is often associated with specific features, such as a unique microbial profile or pattern of host-response (localized to first molars and incisors in some of the cases). Nonetheless, a unifying mechanism has not been established for this condition. AgP...
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Mechanisms of T Cell Dysfunction in Chronic Lymphocytic Leukemia and Viral Associated Carcinoma
DownloadFall 2023
T cell exhaustion compromises anti-tumor immunity, and a sustained elevation of coinhibitory receptors is a hallmark of T cell exhaustion in solid tumors. Similarly, upregulation of co-inhibitory receptors has been reported in T cells in hematological cancers such as chronic lymphocytic leukemia...
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Oral Porphyromonas gingivalis Infection Induces Epigenetic Changes that Promote Persistence of Cardiovascular Disease Risk
DownloadFall 2020
In the last two decades, periodontitis has become recognized as a risk factor for cardiovascular disease (CVD), a term that encompasses many circulatory disorders, often underpinned by atherosclerosis. One of the major questions regarding this association has been whether elimination of...