Search
Skip to Search Results-
Changes in Retinal Mitochondrial Function in Ocular Diseases and a Potential Treatment Using Near-Infrared Light
DownloadFall 2018
Mitochondria are both prominent target and source of reactive oxygen species (ROS). Their role in a wide range of diseases has been gaining a substantial amount of interest, including a number of high-profile ocular diseases. In the present thesis, we investigated the mitochondrial functional...
-
Spring 2021
Purpose. Peroxisomal biogenesis disorders (PBDs) represent a group of recessive conditions that cause severe vision loss, sensorineural hearing loss, neurologic dysfunction, and other systemic abnormalities due to abnormal peroxisomal function. Appropriate therapies are needed as there are no...
-
The risk of hydroxychloroquine retinopathy and the role of the multifocal electroretinogram in screening and monitoring retinal toxicity
DownloadFall 2018
Background: Hydroxychloroquine sulfate (Plaquenil) is a useful, inexpensive drug with a high systemic safety profile. Prolonged use of Plaquenil however causes toxic effects on ocular structures, including the retina. The aim of this study was to determine the role of the multifocal...