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Skip to Search Results- 367Faculty of Pharmacy and Pharmaceutical Sciences
- 4Faculty of Medicine
- 2Faculty of Medicine and Oral Health Sciences
- 1Department of Biomedical Engineering
- 1Department of Medical Sciences
- 1Department of Medicine
- 2Logan, Kerry Jane, 1955-
- 1AL Omair, Omar Abdulrahman
- 1AL-AGILI, MARWA
- 1Abdelmoneim, AS
- 1Abdulsalam Alharbi
- 1Abdussalam, Ali MA
- 15Pharmacokinetics
- 8Cytochrome P450
- 6Cancer
- 6Monoclonal antibodies
- 6Polymeric micelles
- 5Arachidonic acid
- 8El-Kadi, Ayman (Faculty of Pharmacy and Pharmaceutical Sciences)
- 6El-Kadi, Ayman (Pharmacy and Pharmaceutical Sciences)
- 6Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 5Brocks, Dion (Pharmacy and Pharmaceutical Sciences)
- 5Yuksel, Nese (Faculty of Pharmacy and Pharmaceutical Sciences)
- 4Doschak, Michael (Pharmacy and Pharmaceutical Sciences)
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Mechanisms by Which Arachidonic acid Metabolite, Epoxyeicosatrienoic acid Elicit Cardioprotection Against Ischemic Reperfusion Injury
DownloadFall 2011
Epoxyeicosatrienoic acids (EETs) are cytochrome P450 epoxygenase metabolites of arachidonic acid that have cardioprotective properties but the exact mechanism(s) remains unknown. Evidence suggests phosphoinositide 3-kinase (PI3K) and plasma membraneATP-sensitive potassium channels (pmKATP) are...
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Fall 2012
Ischemic heart disease remains a major cause of illness, disability and death worldwide, as such there remains a need for novel pharmacological agents that protect against myocardial ischemia reperfusion (I/R) injury. Epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP) epoxygenase...
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Mechanisms of Pharmacists Interventions on Medication Management and Adherence in Patients with Type 2 Diabetes
DownloadSpring 2014
Optimal management of type 2 diabetes requires a collaborative, team-based approach; however, the role of pharmacists on these teams has not been well-defined. In the first study of this thesis, a systematic review examined components of pharmacist interventions to improve adherence to oral...
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Fall 2015
Ischemic heart Disease (IHD) remains a major cause of illness and death worldwide. Therefore, therapeutic agents to protect against myocardial ischemia are needed. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP) epoxygenase into the biologically active epoxyeicosatrienoic acids...
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Mechanistic Dissolution Modeling of a Poorly Soluble Drug; an Evaluation of Formulation Influence and Simulation Parameters for Enhancing Predictive Capability
DownloadFall 2019
In early drug development, the selection of a formulation platform and decisions on formulation strategies have to be made within a short timeframe and often with minimal use of the active pharmaceutical ingredient (API). At this stage, there is limited information available about the...
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Spring 2020
Medication appropriateness is a fundamental target for the healthcare system, particularly in relation to older adults. Because polypharmacy and multimorbidity are prevalent in older adults, they are more prone to the risks of having an inappropriate medication. They are also more prone to...