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Skip to Search Results- 2Molina-de-Orozco, Vivian Regina, 1955-
- 1Abou Marak Dit Roum, Darine
- 1Aguilar, Hector N
- 1Al-Momany, Abass M T
- 1Al-Zubaidy, Zaidoon A.
- 1Aljunaidy, Mais
- 5Calcium
- 4Calcium channels
- 4Pregnancy
- 3Aortic aneurysm
- 3Biological transport. Regulation.
- 3Blood-vessels. Dilatation.
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Integrative analysis of the developing diaphragm provides a better understanding of congenital diaphragmatic hernia
DownloadFall 2023
Introduction: Congenital Diaphragmatic Hernia (CDH) is a condition that affects 2.3 births every 10,000 and is characterized by an incomplete formation of the diaphragm. As a result of the incomplete development of the diaphragm, the abdominal organs will protrude into the thoracic cavity,...
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Interaction between the S4–S5 linker and C-terminus of TRPP3 channel: functional importance and regulation by PIP2
DownloadFall 2018
As one of the most common genetic renal diseases affecting over 12.5 million people worldwide, the autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in either the PKD1 or PKD2 gene. Transient receptor potential polycystin-3 (TRPP3), a member of the polycystin protein...
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Fall 2020
The mammalian transient receptor potential (TRP) channels, composed of six subfamilies and 28 members, play crucial roles in sensory physiology and malfunctions of TRP channels cause channelopathies. High-resolution structures of TRP channels indicate conformational arrangements showing physical...
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Fall 2021
There are 28 members in the mammalian transient receptor potential (TRP) channel superfamily, which are divided into six subfamilies, TRPA/C/M/ML/P/V, and play distinct sensory roles in response to various environmental stimuli. High-resolution structures of various TRP channels show a number of...
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Intrauterine cooperativity: amplification between ligands, cells, and tissues to transition the uterus for parturition
DownloadFall 2018
Birth is a complex biological event requiring genetic, cellular and physiological changes to the uterus, resulting in a uterus activated for completing the physiological processes of labour. We define the change from the state of pregnancy to the state of parturition as uterine transitioning,...
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Investigating Myocardial PI3Kα Signaling in Models of Ischemia Reperfusion and Cardiotoxic Cancer Therapies
DownloadSpring 2017
Background. Phosphoinositide 3-kinase (PI3K) is a lipid kinase that functions as a central intracellular signaling transduction node, receiving input from cell receptors and initiating a cascade of cellular signaling that regulates and integrates central cellular processes such as glucose uptake,...