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The Efficacy of Using Small Molecule Ice Recrystallization Inhibitors to Enable the Frozen Storage of Livers
DownloadFall 2020
The limited storage times afforded by hypothermic preservation at 0 °C to 4 °C imposes several logistic constraints on the organ transplant network. In the case of livers, two-thirds of wait listed patients do not receive transplants in Canada, which is partially attributed to the 12 h storage...
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The Role of Extracellular Vesicles and Red Blood Cell Manufacturing Methods on Transfusion-Related Immunomodulation
DownloadSpring 2019
Transfusion of red blood concentrates (RCCs) is a lifesaving procedure. Nonetheless, a number of studies have revealed that transfusion of RCC products is still associated with increased risk of serious clinical outcomes. Additionally, studies demonstrating the deleterious consequences of...