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Skip to Search Results- 33Mass-spectrometry
- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Fall 2016
This thesis reports a facile method to stabilize colloidal self-assembled (CSA) 310 and 50 nm nanoparticles packed in microchannels for high speed size-based separation of denatured proteins. Silica nanoparticles, self-assembled in a network of microfluidic channels, were stabilized with a...
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Fall 2012
Transition metal-mediated E–H (E = Si, Ge) bond activation plays a pivotal role in industrially important processes, such as hydrosilylation and dehydrogenative coupling of organosilanes. Activation of these bonds by mono-metallic complexes is well studied, however, E–H bond activations in...
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Stereoselective Synthesis of β-Aminoalkylboronic Acid Derivatives Using 1,1-Diboron Compounds
DownloadSpring 2020
As an important class of chiral alkylboron compounds, α-aminoalkylboronic acids display distinct utility in medicinal chemistry as a bioisostere of α-amino acids and α-amino aldehydes, which is highlighted by the commercialization of two anticancer drugs (bortezomib and ixazomib) and one...
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Spring 2020
Polycyclic aromatic hydrocarbons (PAHs), or more specifically pentacene derivatives, are promising candidates for solar energy conversion. Pentacenes can undergo π-stacking in solution and, consequently, can be poorly soluble. Furthermore, the pentacene moiety can react with oxygen, and it can...
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Stimuli-Responsive Microgel-Based Materials and Their Assembly for Controlled Drug Delivery and Sensing Systems
DownloadFall 2020
Conventional drug delivery methods result in a burst of drug concentration in plasma, followed by a decline, which leads to issues with maintaining drug concentrations in the therapeutic range. Furthermore, this high plasma concentration can lead to undesirable (and dangerous) side effects that...
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Stimuli-Responsive Microgel-Based Systems and Their Application for Controlled Drug Release
DownloadFall 2017
Stimuli-responsive polymers have found their way into numerous materials and devices for myriad applications that can solve problems related to human health and the environment. In this dissertation, the work covers the general scope of stimuli-responsive polymers, with a special focus on...