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Investigations of interactions between membrane and PEI/siRNA nanoparticles and their implication for non-viral gene delivery
DownloadSpring 2021
Cell entry of polynucleotide-based therapeutic agents can be promoted by nanoparticle (NP) mediated delivery. This dissertation investigates membrane penetration of polynucleotide NPs, using mainly computational approaches, accompanied by some experiments. Major emphasis was placed on...
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Spring 2021
Asphaltenes are the heaviest and most polar group of molecules in crude oil. Colloidal behaviors of asphaltenes, including the aggregation and interfacial behaviors, have impacts on many petroleum production processes. For example, the aggregation of asphaltenes can lead to problems such as...