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Skip to Search Results- 2Chun, Justin
- 1Aktary, Zackie M
- 1Anderson, Andrea Marie
- 1Anderson-Baron, Matthew N
- 1Armstrong, Heather K
- 1Baier, Alicia
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Spring 2012
Mast cells are tissue-resident immune cells that undergo exocytosis upon activation, releasing potent immunoregulatory molecules that initiate inflammatory responses. Here, I investigated the role of the hematopoietic specific Rho GTPase, Rac2, and the ubiquitous, Rac1, on mast cell exocytosis....
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Spring 2019
In yeast, subtelomeric chromatin is silenced and positioned at the inner nuclear membrane (INM) through the interaction of proteins that comprise the heterotrimeric SIR complex with INM proteins. Telomeres reside primarily at the INM using partially redundant tethering mechanisms mediated by the...
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Understanding the evolution of the membrane trafficking system in diverse eukaryotes through comparative genomics and transcriptomics
DownloadSpring 2018
Single-celled organisms represent the majority of eukaryotic diversity. Recent advances in sequencing technologies have been critical for understanding the evolutionary biology and cell biology of microbial eukaryotes. Comparative genomic analyses have shown that many genes that underlie...
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Fall 2018
Cells require the ability to modulate function in response to their surroundings so that they are able to contribute to the survival of the organism. A key mechanism that allows tunable responses to changes in environment is by differential control of gene expression by transcriptional...