Search
Skip to Search Results- 2Lohmeier, Elke Monika, 1955-
- 2Veldhoen, Richard
- 1ALSHUMAIMERI, NADA A.
- 1Acevedo Morantes, Claudia Y
- 1Aderibigbe, Ayodeji O.
- 1Ahsan, Irfan.
-
Fall 2018
Sudden unexplained death (SUD) is a term used when comprehensive medical examination and autopsy fail to find a conclusive cause of sudden death. In cases of SUD, post-mortem molecular and genetic evaluation methods have helped identify ion channel abnormalities leading to arrhythmias as cause....
-
Fall 2013
In human cells, oscillations in calcium concentration serve as a mechanism for controlling a variety of physiological processes including muscle contraction and relaxation. The sarcoplasmic reticulum (SR) is a calcium storage organelle in muscle cells that contains a calcium pump (SERCA) required...
-
Fall 2012
The movement of calcium across sarcoplasmic reticulum (SR) membranes is essential in the contraction-relaxation cycle of muscle. An influx of calcium into the muscle cell from the SR triggers muscle contraction and its removal by the sarco(endo)plasmic reticulum calcium ATPase (SERCA) causes...
-
Fall 2023
When calcium enters the cytosol of a muscle cell from the SR, it initiates muscle contraction, while its removal by the sarco(endo)plasmic reticulum calcium ATPase (SERCA) induces muscle relaxation. SERCA's activity is regulated by Phospholamban (PLN), which can reversibly inhibit its apparent...
-
Molecular Mechanisms of the Activation of the Pattern Recognition Receptor Dectin-1 and its Induction of Immune Responses
DownloadFall 2014
In the past two decades, a rising number of fungi have emerged as serious human pathogens and the incidence of invasive fungal infections has increased enormously. Millions of people contract fungal diseases that kill at least as many people as tuberculosis or malaria, yet the global burden of...