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Exploring Novel Therapies for Motor and Non-Motor Symptoms in a Mouse Model of Multiple Sclerosis
DownloadSpring 2016
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by neurodegeneration, inflammation and demyelination. Symptoms of multiple sclerosis not only include motor deficits, but also secondary symptoms of pain, depression and anxiety. The purpose of...
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The glutamate transporters' role in neuropathic pain and cognitive deficits in an animal model of multiple sclerosis
DownloadFall 2013
Multiple Sclerosis (MS) is a chronic disease of the central nervous system characterized by demyelination, inflammation and axonal injury. Chronic pain and cognitive deficits affect a large percentage of MS patients. While a number of animal models are available to study the pathophysiology of...
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Fall 2014
Fragile X Syndrome (FXS) is the most common genetic cause of Intellectual Disability, affecting 1 in 4000 boys and 1 in 6000 girls. Work in our lab using Drosophila melanogaster and since replicated in the mouse model has shown that excess protein synthesis is a major mechanism connecting the...