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Disrupting the Repeat Domain in Zebrafish Premelanosome Protein (Pmela) to Probe an Evolutionary Puzzle and Model Pigmentary Glaucoma
DownloadFall 2022
The premelanosome protein (PMEL) is a functional amyloid that provides a scaffold for the even distribution of melanin and provides structure for the organelle that contains them, the melanosome. Mutations in this protein cause a plethora of phenotypes that extend beyond affecting strictly...
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