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Unveiling the pathway for the nuclear translocation of the large mitochondrial enzyme Pyruvate Dehydrogenase Complex (PDC)
DownloadSpring 2021
Pyruvate dehydrogenase complex (PDC) is a mitochondrial enzyme that links glycolysis to oxidative phosphorylation by decarboxylating glucose-derived pyruvate to produce acetyl-CoA that is used in the Krebs cycle. PDC was initially thought to reside only in the mitochondrial matrix but we recently...
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