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New insights into the N-end Rule Pathway: from the substrate recognition to its selective inhibition
DownloadFall 2019
The N-end rule represents a crucial proteolytic pathway which regulates in vivo half-life of a protein by the identity of its N-terminal residues. As such, the instability of the substrate is conferred by the ability of the cellular machinery to recognize the N-terminal amino acid and target the...
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