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Assessing Colloidal Stability of Pharmaceutical Suspensions with a Shadowgraphic Imaging Method
DownloadFall 2019
The colloidal stability of pharmaceutical suspensions is an important attribute that needs to be carefully characterized in order to ensure designed product quality. In the field of respiratory drug delivery, pharmaceutical suspensions contained in pressurized metered-dose inhalers (pMDIs) are...
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Development of a Thermostable Tuberculosis Vaccine Candidate Suitable for Pulmonary Delivery through Particle Engineering
DownloadFall 2020
Tuberculosis (TB) is a preventable and curable highly infectious respiratory disease that is responsible for the deaths of approximately 1.5 million people every year. However, vaccination programs are hindered by refrigeration requirements for vaccines during transportation and storage....
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Engineering Stable Bacteriophage Dosage Forms Active Against Antibiotic-Resistant Bacteria for Respiratory Delivery and Food Safety Applications
DownloadFall 2019
The topic of this thesis is the engineering of stable bacteriophage dosage forms that are active against antibiotic-resistant bacteria for applications in respiratory delivery and food safety. Experimental methods and theoretical models are developed to test and understand the effects that...
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Fall 2018
This thesis is concerned with the mechanisms by which evaporating droplets containing dissolved or suspended solids transform into dry particles, and emphasizes applied research in the area of inhaled drug delivery. The main focus is on understanding and quantifying the relationships between the...