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Functional Assessment on the Differential Effect of Mutant p53-Plakoglobin Interaction in Carcinoma Cells
DownloadSpring 2023
p53 transcriptional factor and tumor suppressor protein is mutated in over 50% of all cancers and most metastatic tumors. Majority of p53 mutations are single missense mutation and occur in the DNA-binding domain (DBD). The six most common missense mutations in the p53 DBD are known as “hot...
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