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Augmenting Hypothermia Therapy for Hypoxic-Ischemic Encephalopathy in Neonates: Localizing Drug Delivery using pH and Temperature Responsive Nanoparticles
DownloadFall 2022
The obstruction of blood flow to regions of an infant brain leads to a reduction of oxygen and essential nutrients, causing what is known as hypoxic-ischemic (HI) damage to that region. Presently the only treatment available for affected neonates is hypothermia: head or whole-body cooling....
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Hemodynamic Differences in Recovery Following Chest Compression with Asynchronous Ventilation Using Chest Compression Rates of 90/min, 100/min, or 120/min in a Porcine Model of Neonatal Asphyxia
DownloadSpring 2020
Extensive neonatal resuscitation that involves chest compressions is an uncommon event impacting approximately 0.1% of term newborns, and up to 15% of preterm newborns. Despite best resuscitation efforts birth asphyxia results in approximately one million deaths annually worldwide. Neonatal...