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Fall 2024
Astrocytes can store excess fatty acids in lipid droplets to avoid lipotoxicity. Fatty acids can be released from lipid droplets and catabolized to generate energy in the mitochondria. We previously found reduced astrocytic lipid droplets and increased transport of fatty acids into the...
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Impacts of non- and whole-fat milk supplementation on metabolic dysfunction-associated steatotic liver disease (MASLD) in C57BL/6 mice
DownloadFall 2024
The pathophysiology behind metabolic dysfunction-associated steatotic liver disease (MASLD) and mechanisms underlying the progression of the disease are highly complex, complicating treatment options, leaving diet and weight loss as the standard of care. Functional foods can mitigate MASLD...
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Fall 2020
Peroxisomes are organelles responsible for processing lipids and managing reactive oxygen species. A conserved family of genes called peroxisome biogenesis factors (Peroxin, Pex) encode proteins necessary for peroxisome biogenesis and function. In yeast and mammals, PEROXIN7 (PEX7) acts as a...
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Role of Betaine Homocysteine Methyltransferase in Regulating Lipid Metabolism in McArdle RH7777 Cells
DownloadFall 2013
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. It is a clinical pathological state characterized by the accumulation of triacylglycerol (TG) in hepatocytes. It can progress to non-alcoholic steatohepatitis (NASH) and in some cases to fibrosis...