This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Exploratory study of egg white hydrolysate mechanisms of action in insulin sensitive tissues of high fat diet-induced insulin resistant rats
DownloadSpring 2019
Background: Chronic diseases related to the metabolic syndrome, such as type 2 diabetes and hypertension lead to complications when not treated properly. Natural approaches able to tackle multiple aspects of the metabolic syndrome and cause minimal side effects are desired. Bioactive peptides are...
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Exposure to Allergens and Proinflammatory Mediators Modulate Airway Epithelial Cell Innate Responses, Metabolism, and Physiology
DownloadFall 2024
Lungs and airways health and protection depend on the integrity of airway epithelium. Insulin is a growth hormone that through activation of several signaling pathways play a central role to maintain cellular growth and activate metabolism. Airway epithelium is in constant exposure to inhaled...
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Long-term effects of early-life gut microbiota perturbations on pancreatic islet development
DownloadFall 2021
Impaired secretion of insulin from pancreatic beta-cells, along with loss of cell mass, is one of the hallmarks of the pathogenesis of type 2 diabetes, a metabolic disorder characterized by chronic hyperglycemia. In humans, beta-cells’ ability to secrete insulin in response to glucose is acquired...
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Fall 2024
Obesity and associated insulin resistance (IR) represent a significant global health burden. Emerging evidence suggests that obesity is accompanied by impaired adaptive immunity. B cells contribute significantly to adaptive immunity, and the dysregulation of B cell function in obese individuals...
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The role of obesity and insulin resistance in modulating immune cell function in cancer and liver disease
DownloadFall 2023
Obesity and associated insulin resistance (IR) represent a significant global health burden, and predispose individuals to develop various diseases, including cancer and liver diseases. Heightened inflammation during obesity can on the one hand exacerbate liver inflammation, while on the other,...