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Developing an M3 Antagonist for Molecular Imaging of Muscarinic Acetylcholine Receptors in Breast Cancer
DownloadFall 2021
The lack of the three targeted receptors, estrogen, progesterone, and the human epidermal growth factor receptor 2, causes difficulty in treating triple negative type cancers. Most often, patients with this type of malignancy have a low chance of survival. The focus of this work will be on...
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Spring 2021
Information is transmitted between neurons through the flow of different ions and the release of neurotransmitters at speeds on the order of milliseconds. The advent of genetically encoded fluorescent protein (FP)-based optical indicators for neuronal activity, which can be precisely targeted...
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Tracer Development for the Molecular Imaging of Breast Cancer: Synthesis and Biological Evaluation of C-3 Modified 2,5-Anhydro-D-mannitol Derivatives as Potential Tracer Molecules
DownloadSpring 2016
Mammography is the most frequently used imaging method for the detection of breast cancer. Despite the key role of mammography in the breast cancer detection, false-negative diagnosis by mammograms ranges from 4 to 34%. Positron emission tomography (PET), a tracer based molecular imaging method...