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A Study of Potential Plasma Biomarkers of Disease Conversion and Progression in Multiple Sclerosis
DownloadFall 2020
Multiple sclerosis (MS) is a complex and heterogeneous disease of the central nervous system (CNS) characterized by leukocyte infiltration, myelin damage, local gliosis, and axonal injury. Relapsing-remitting MS (RRMS) is the most common disease course. Although the pathogenesis remains unclear,...
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Fall 2024
Astrocytes can store excess fatty acids in lipid droplets to avoid lipotoxicity. Fatty acids can be released from lipid droplets and catabolized to generate energy in the mitochondria. We previously found reduced astrocytic lipid droplets and increased transport of fatty acids into the...
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Effect of starter culture on accumulation of taste active amino acids, free fatty acids, and on survival of pathogenic Escherichia coli in dry fermented beef sausages
DownloadSpring 2018
The accumulation of taste active compounds during ripening determines the taste of fermented meats; however, the contribution of defined starter cultures to glutamate during sausage ripening remains unknown. This study investigated the role of lactic acid bacteria and Staphylococcus carnosus on...
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Effects of Rumen-Protected Glutamate Supplementation during the Periparturient Period on Digestibility, Inflammation, Metabolic Responses and Performance in Dairy Cows
DownloadSpring 2022
Dairy cows often experience negative energy balance, fat mobilization and inflammation after calving, which increases health problems. Glutamate (Glu) is a primary energy source for the small intestine and a glucogenic amino acid in the liver, and feeding Glu enhances gastrointestinal growth,...
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Fall 2020
In the perimenopausal period, an event marked by end of menstrual cycle regularity, women are at a greater risk of either experiencing a reoccurrence of a major depressive episode (MDE), or presenting with their first MDE. This risk is greater in women with a history of mood vulnerability related...