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Colorectal Cancer Small Extracellular Vesicles Induce Matrix Metalloproteinase Expression, an Invasion-Promoting Phenotype, and CD147-Dependent MAPK/AP-1 Activation in Macrophages
DownloadFall 2020
Exosomes and small microvesicles are types of small extracellular vesicle (sEVs) secreted by cancerous and normal cells. sEVs are filled with cargo from cancer cells that may affect both nearby and distant tissues. sEVs from colorectal cancers that enter blood vessels draining the intestine will...
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Role of gangliosides in extracellular vesicle secretion in wild-type and Huntington's disease cell models
DownloadFall 2020
Gangliosides are sialic acid containing glycosphingolipids highly enriched in the brain that play vital roles in intercellular communication, cell signalling and calcium homeostasis. A decrease in the ganglioside levels in the brain has been associated with several neurodegenerative diseases....