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Cytoskeletal Remodeling and Exocytosis During Mast Cell Activation is Controlled by the RhoA GEF, GEF-H1
DownloadFall 2021
Mast cells are tissue-resident immune cells that play important roles in health and diseases. Mast cells release their granule contents under antigen-stimulation via the FcεRI signaling pathway. The process of regulated exocytosis in mast cells is known as degranulation which participates in...
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Fall 2018
Mast cells (MCs) are tissue resident innate immune cells. They are recognized for their immunoregulatory roles in the regulation of innate and adaptive immunity. Aberrant activation and responses of MCs result in inflammatory disorders like allergies. Thus, the biological pathways that control MC...