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Engineering agarolytic enzymes into Bacteroides thetaiotaomicron for the development of a drug delivery system with algal polysaccharide-derived capsules
DownloadSpring 2020
The microbiota of the distal gastrointestinal tract (GIT) of monogastric animals plays a vital role in maintaining host health, such as releasing energy and nutrients from dietary polysaccharides that are otherwise indigestible by human enzymes. These dietary polysaccharides can be coupled to the...
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Evaluation of fecal microbial transplant as a treatment method for disruption of the gut microbiota associated with short bowel syndrome in neonates.
DownloadFall 2021
Background Short bowel syndrome (SBS) is the leading cause of intestinal failure (IF), wherein either the function of the intestines is suboptimal, or length has been reduced due to congenital or acquired conditions, such that parenteral nutrition (PN) is required for >6 weeks. The most common...