This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
Search
Skip to Search Results-
Cardiac Manifestation and Clinical Management Strategies in Patients with Fabry Disease and Muscular Dystrophy
DownloadFall 2023
Background Fabry disease (FD) and Muscular dystrophy (MD) are hereditary disorders with a high burden of heart disease recognized as a common cause of morbidity and mortality. The routine clinical care management of rare genetic diseases is complicated by extensive multisystem involvement, lack...
-
Spring 2019
Dramatic maturational changes occur in heart energy metabolism in the fetal to newborn transition, most predominantly marked by a decrease in glycolysis and an increase in fatty acid oxidation which then becomes the major energy providing substrate for the heart after birth. However, in the...
-
Spring 2012
The surgical repair of congenital heart defects (CHDs) often requires a bloodless/motionless field achieved by arresting the neonatal heart and exposing it to a period of ischemia. Metabolic manipulation, such as suppression of fatty acid (FA) oxidation, improves post-ischemic functional recovery...