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2016-01-01
Deanna R Funk, Normand G Boulé, Peter A Senior, Jane E Yardley
Islet transplantation (ITx) is effective in preventing severe hypoglycemia by restoring glucose-dependent insulin secretion in type 1 diabetes (T1D), but may not normalize glucose regulation. Studies suggest that physical activity plays a role in maintaining β-cell mass and function in...
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Improving Islet Function and Engraftment by Co-culturing Islets with Mesenchymal Stem Cells and the Formation of Pseudoislets
DownloadFall 2018
Islet transplantation has proven to be efficacious in preventing severe hypoglycemia and restoring insulin independence in selected patients with type 1 diabetes. The well-established procedure has gained popularity due to notable refinements over the past two decades. However, islet...