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Skip to Search Results- 1Concordia University of Edmonton
- 1Concordia University of Edmonton/Independent Research Reports in Undergraduate Biology and Environmental Science (Concordia University of Edmonton)
- 1Graduate and Postdoctoral Studies (GPS), Faculty of
- 1Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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2016-11-04
Background: Prader-Willi syndrome (PWS) is a multigene disorder commonly associated with hyperphagia and obesity. Children with PWS have increased fat mass and decreased lean mass before the onset of hyperphagia and obesity. Severe hypotonia and reduced muscle strength are typically present in...
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The lysosomotropic agent siramesine induces cell death in prostate cancer cells and synergizes with the tyrosine kinase inhibitor lapatinib
DownloadFall 2024
Prostate cancer is the most diagnosed cancer affecting Canadian men. Prostate tumors that progress from localized disease to advanced stages show resistance to standard therapy, a major problem that requires alternative treatments. One new treatment possibility is targeting lysosomal membrane...