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- 11Graduate Studies and Research, Faculty of
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A role for the nuclear pore complex protein Nup170p in defining chromatin structure and regulating gene expression
A role for the nuclear pore complex protein Nup170p in defining chromatin structure and regulating gene expression
Download2012-04
The spatial organization of chromosomal loci within the nucleus can have a significant influence on transcriptional activity. Transcriptionally active genes are generally positioned within the nuclear interior. By contrast, the positioning of genes at the nuclear periphery is often correlated...
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Development of technological alternatives to produce renewable fuels from oleaginous microorganisms
Download2014-11
Microbial lipids are a promising feedstock for the production of renewable fuels. However, use of microbial lipids has been hindered due to challenges in the cultivating and processing of microbes. Thus, innovative technologies are required to enhance the feasibility of integrating oleaginous...
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Divergent genes for translation inition factor elF-4A are coordinately expressed in tobacco
Download1991
Kuhlemeir, Cris, Holfmann, Sylvia, Owtrim, George W.
Three cDNA clones coding for eukaryotic translation initiation factor 4A, elF-4A, were isolated from a Nicotiana plumbaginifolia root cDNA library by heterologous screening. The clones comprise two distinct gene classes as two clones are highly similar while the third is divergent. The genes...
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Exploring the role of the thioredoxin system, peroxiredoxins and glutaredoxins in aluminum and cadmium tolerance in yeast and Arabidopsis thaliana
Download2011-11
Aluminum (Al) and cadmium (Cd) are non-redox active metal ions of agricultural importance. Both are able to induce oxidative damage as a mechanism of toxicity. To increase our understanding of the mechanisms of Al and Cd toxicity and tolerance in plants, the potential role of antioxidant enzymes...
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Functional and Topological Analysis of Acyl-CoA:Diacylglycerol Acyltransferase 2 From Saccharomyces cerevisiae
Download2011-06
Acyl-CoA:diacylglycerol acyltransferase (EC 2.3.1.20, DGAT or DAGAT) is a membrane protein found mainly in the endoplasmic reticulum (ER). It catalyzes the final step in the biosynthesis of triacylglyerol (TAG or TG), which is the principal repository of fatty acids for energy utilization and...
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How studying the interaction of Sir4 with a subset of Nups uncovered a new chromatin bound complex.
Download2017-11:Fall 2017
The nucleus is the defining feature of eukaryotic cells and its major function is to house the cell’s genome and segregate it from the surrounding cytoplasm. The membranes encapsulating the nucleus constitute the nuclear envelope (NE). The interactions between the NE and chromatin facilitate the...
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In vivo and in vitro evidence for biochemical coupling of reactions catalyzed by lysophosphatidylcholine acyltransferase and diacyglycerol acyltransferase
Download2015
Greer, Michael S., Pan, Xue, Weselake, Randall J., Chen, Guanqun, Zou, Jitao, Caldo, Kristian Mark P., Kazachkov, Michael
Seed oils of flax (Linum usitatissimum L.) and many other plant species contain substantial amounts of polyunsaturated fatty acids (PUFAs). Phosphatidylcholine (PC) is the major site for PUFA synthesis. The exact mechanisms of how these PUFAs are channeled from PC into triacylglycerol (TAG) needs...
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Inactivation of Saccharomyces cerevisiae and Candida humilis in Potassium Phosphate Buffer by Pulsed Electric Fields
Download2016-06
Pulsed electric field (PEF) is a promising athermal food preservation technology, having the potential to provide a better balance between food safety and food quality. But the high cost of PEF treatment has limited the commercial application of this technology. The aim of this MSc thesis...