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Spring 2015

Acosta Amador, Paula N

The gram negative bacterial cell envelope is composed of the outer membrane, the periplasm and the inner membrane. These compartments are exposed directly to changes in the environment that are sensed and adapted to through different signaling transduction pathways. This often occurs through...

Fall 2020

Hussain, Nora A.S.

The type VI secretion system (T6SS) is a contact-dependent molecular weapon used by bacteria to transport a variety of effectors into neighbours. Attacked cells must have immunity proteins specific to each incoming effector in order to neutralize their cytotoxic effects. Vibrio cholerae, a...

Fall 2017

Kirchberger, Paul C.

Vibrio cholerae, because of its role as the causative agent of cholera pandemics, is an extraordinarily well studied microorganism. Decades of research have uncovered a plethora of molecular mechanisms and a wealth of genomic information related to the organisms’ lifestyle as a pathogen. V....

Spring 2022

Islam, Mohammad Tarequl

Phylogenomic structuring of the Vibrio cholerae clade is an important area of study in the context of the alarming spike of human morbidities due to environmental pathogens around the world. Even after decades of research, the structuring of natural populations of V. cholerae and its sister...

Fall 2019

Nasreen, Tania

Cholera, a severe life-threatening waterborne diarrheal disease, has been endemic to the Ganges delta for centuries. Vibrio cholerae, the causative agent of this disease, is a natural inhabitant of brackish water. Amongst the 200 serogroups identified so far, only O1 and O139 were found...