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- 2Troponin I
- 1Acute coronary syndrome
- 1Binding affinity
- 1Bradford Hill considerations
Building Evidence to Assess a Drug Safety Signal: the Association between Sulfonylureas and Adverse Cardiovascular EventsDownload
All drugs have the potential to cause adverse events that can result in hospitalization or death. In order to protect the public health, it is critical to employ methods to detect and assess adverse drug events in a timely manner. One of the most controversial and long standing drug safety issue...
Intracellular regulation of matrix metalloproteinase-2 activity: the roles of caveolin-1 and troponin I phosphorylationDownload
Matrix metalloproteinase‐2 (MMP‐2) was recently revealed to have targets and actions within the cardiac myocyte. In ischemia/reperfusion (I/R) injury, MMP‐2 is activated and degrades troponin I (TnI) and α‐actinin. The regulation of intracellular MMP‐2 activity is relatively unknown and is thus...