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Spring 2019
Phosphatidylcholine (PC), the most abundant phospholipid in eukaryotic cells, is an important component of cellular membranes and lipoprotein particles. The enzyme CTP: phosphocholine cytidylyltransferase (CT) regulates de novo PC synthesis in response to changes in membrane lipid composition in...
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Fall 2024
Background: Dyslipidemia is a common characteristic in both diabetes and obesity, due in part to elevated triglyceride (TG)-rich very-low density lipoprotein (VLDL-TG) secretion from the liver. Excessive levels and/or action of glucocorticoids (GCs) is also observed in these metabolic diseases...
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Roles of Acyl-CoA:Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Hepatocytes
DownloadFall 2015
Triacylglycerol (TG) metabolism with its high-energy potential is stringently regulated. Unbalanced TG regulation, either too much TG that overwhelms cellular storage capacity or too little TG due to defects in adipogenesis, is associated with various metabolic disorders. TG can be exported from...